Neurogenesis and Neural Plasticity (Current Topics in Behavioral Neurosciences)

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Neural Plasticity

How it Works Discover Feeds. Differential effects of social and physical environmental enrichment on brain plasticity, cognition, and ultrasonic communication in rats The Journal of Comparative Neurology Jun 1, Get PDF. Get paper from. Entire Dentate Gyrus. Structure of Dentate Gyrus.

Neurogenesis and hippocampal plasticity in adult brain.

Sound Communication, Animal. Up-Regulation Physiology. Neuronal Plasticity. Anxiety Disorders. Paper Details.

References 90 Citations Autoradiographic localisation of substance P NK1 receptors in human primary visual cortex Brain Research June 1, Laura Kus Dominic P Geraghty. More hippocampal neurons in adult mice living in an enriched environment Nature April 3, Gerd Kempermann Fred H. Ngan Vo Soren D Impey. Enriched environments, experience-dependent plasticity and disorders of the nervous system Nature Reviews. Neuroscience September 1, Jess Nithianantharajah , Anthony John Hannan. Dopamine depletion impairs precursor cell proliferation in Parkinson disease Nature Neuroscience July 1, New neurons in the dentate gyrus are involved in the expression of enhanced long-term memory following environmental enrichment The European Journal of Neuroscience January 1, Elodie Bruel-Jungerman Claire Rampon.

Joachim Silber John Graeme Hodgson. The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents Neuroscience and Biobehavioral Reviews February 12, Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory Journal of Neurobiology June 15, Role of histone acetylation in long-term neurobehavioral effects of neonatal Exposure to sevoflurane in rats Neurobiology of Disease April 4, Min Jia Jian-Jun Yang.

The Athlete's Way. For over a decade, neuroscientists have been trying to figure out how neurogenesis the birth of new neurons and neuroplasticity the malleability of neural circuits work together to reshape how we think, remember, and behave. The January findings were published in the journal eLife. For their latest UAB study, Linda Overstreet-Wadiche and Jacques Wadiche —who are both associate professors in the University of Alabama at Birmingham Department of Neurobiology—focused on neurogenesis in the dentate gyrus region of the hippocampus.

The dentate gyrus is an epicenter of neurogenesis responsible for the formation of new episodic memories and the spontaneous exploration of novel environments, among other functions. There are only two major brain regions that are currently believed to have the ability to continually give birth to new neurons via neurogenesis in adults; one is the hippocampus long-term and spatial memory hub the second is the cerebellum coordination and muscle memory hub.

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Notably, granule cells have the highest rate of neurogenesis. Both the hippocampus and cerebellum are packed, chock-full with granule cells. To read a wide range of Psychology Today blog posts on the topic click on this link. As a side note, the olfactory bulb is the only other subcortical brain area known to have high rates of neurogenesis. The latest UAB research suggests that newborn neurons play a role in expediting this process by "winning out" in a survival of the fittest type of neuronal battle against their more elderly or worn out counterparts.

How worn and dusty, then, must be the highways of the world, how deep the ruts of tradition and conformity! From a psychological standpoint, the latest UAB discovery presents the exciting possibility that when adult-born neurons weave into existing neural networks that new memories are created and older memories may be modified. Granule cells in the dentate gyrus are part of a neural circuit that processes sensory and spatial input from other areas of the brain.

By integrating sensory and spatial information, the dentate gyrus has the ability to generate unique and detailed memories of an experience.

Environmental Enrichment and Neuronal Plasticity - Oxford Handbooks

Before this study, Overstreet-Wadiche and her UAB colleagues had a few basic questions about how the newly born granule cells in the dentate gyrus function. They asked themselves two specific questions:. Through a series of complex experiments with mice, Overstreet-Wadiche et al. So, the process of adult neurogenesis not only adds new cells to the network, it promotes plasticity of the existing network. It will be interesting to explore how neurogenesis-induced plasticity contributes to the function of this brain region.

Neurogenesis is typically associated with improved acquisition of new information, but some studies have also suggested that neurogenesis promotes 'forgetting' of existing memories. I describe my philosophy in the Introduction to The Athlete's Way ,.

The Athlete's Way does not focus just on sculpting six-pack abs or molding buns of steel. We are more interested in bulking up your neurons and reshaping your synapses to create an optimistic , resilient , and determined mindset. The goal is transformation from the inside out.

What is NEUROPLASTICITY? What does NEUROPLASTICITY mean? NEURPLASTICITY meaning & definition

My mission is to get this message to you so that you can use neurobiology and behavioral models to help improve your life through exercise. My conviction is strong and authentic because I have lived it.


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If anything, it was believed that people could only lose neurons or "kill brain cells" as we got older. This is fascinating stuff! These are exciting times in neuroscience. Stay tuned for future empirical evidence and scientific research on neurogenesis and neuroplasticity in the months and years ahead.

Adult-born neurons modify excitatory synaptic transmission to existing neurons. This means so much to someone like myself.

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